Biodegradable microparticles as drug delivery system for NO donors ruthenium nitrosyl complexes
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چکیده
منابع مشابه
Ruthenium complexes as NO donors for vascular relaxation induction.
Nitric oxide (NO) donors are substances that can release NO. Vascular relaxation induction is among the several functions of NO, and the administration of NO donors is a pharmacological alternative to treat hypertension. This review will focus on the physicochemical description of ruthenium-derived NO donor complexes that release NO via reduction and light stimulation. In particular, we will di...
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A cationic mononitrosyl dinuclear ruthenium complex was prepared by removing one NO ligand of a dicationic dinitrosyl ruthenium complex using NaN3. Reduction and oxidation reactions of the mononitrosyl complex led to the isolation of a neutral nitrosyl-bridged complex and a dicationic mononitrosyl complex, respectively, as expected from the cyclic voltammogram. According to the electron count, ...
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During the last decade, the US Food and Drug Administration (FDA) have regulated a wide range of products, (foods, cosmetics, drugs, devices, veterinary, and tobacco) which may utilize micro and nanotechnology or contain nanomaterials. Nanotechnology allows scientists to create, explore, and manipulate materials in nano-regime. Such materials have chemical, physical, and biological properties t...
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Two novel water soluble ruthenium(II) complexes [Ru(bpy)(2)(bqbg)](2+) and [Ru(phen)(2)(bqbg)](2+) have been structurally characterized and their DNA condensation activity, cytotoxicity, and cellular uptake studies of DNA condensates as potential non-viral DNA carriers were evaluated.
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ژورنال
عنوان ژورنال: The FASEB Journal
سال: 2006
ISSN: 0892-6638,1530-6860
DOI: 10.1096/fasebj.20.4.a101-c